… effect of arachidonylcyclopropylamide, a cannabinoid 1 receptor agonist & lignocaine, a local anaesthetic agent, following direct intrawound administration in rats

R Kumar, P Prasoon, M Gautam… - Indian Journal of Medical …, 2016 - journals.lww.com
… antinociceptive effect of type 1 cannabinoid receptor (CB1r) … AM251 alone significantly
reversed thermal hyperalgesiaattenuated thermal hyperalgesia and mechanical allodynia. It may …

TARGETING THE ENDOCANNABINOID SYSTEM WITH ORTHOSTERIC AND ALLOSTERIC CANNABINOID LIGANDS TO REDUCE CORNEAL PAIN AND …

D Thapa - 2019 - dalspace.library.dal.ca
… orthosteric and allosteric cannabinoid receptor ligands using … can reduce the expression of
c-Fos leading to attenuation of c… (AM251) or 5-HT1A receptor (WAY100635) antagonists were …

Cannabinoid 1 receptor knockout mice display cold allodynia, but enhanced recovery from spared-nerve injury-induced mechanical hypersensitivity

A Sideris, B Piskoun, L Russo, M Norcini… - Molecular …, 2016 - journals.sagepub.com
… an antagonist of CB1R administered systemically significantly reduces mechanical and
thermal hyperalgesia … pain relief and recovery after peripheral nerve and burn injuries, 16–18 …

Resolvin D1 attenuates mechanical allodynia after burn injury: Involvement of spinal glia, p38 mitogen-activated protein kinase, and brain-derived neurotrophic factor …

X Zhao, X Li, H Guo, P Liu, M Ma, Y Wang - Molecular Pain, 2023 - journals.sagepub.com
… downregulated BDNF/TrkB following burn injury. Furthermore, … might attenuate mechanical
allodynia after burn injury by … that burn injury in rats resulted in hyperalgesia and allodynia

Nonopioid GTS-21 mitigates burn injury pain in rats by decreasing spinal cord inflammatory responses

Y Zhou, Y Leung-Pitt, H Deng, Y Ren, Z You… - Anesthesia & …, 2021 - journals.lww.com
… MLA is a specific α7AChR blocker for 1 wk. Preliminary … GTS-21 attenuates postburn
mechanical allodynia in young … GTS-21 attenuated postburn heat hyperalgesia in young rats. A, …

Endogenous analgesic systems and neuropathic pain

E Sokolaj - 2023 - ses.library.usyd.edu.au
… , such as naloxone and naltrexone, attenuate the stress-… by cannabinoid CB1 knockout
and antagonists, such as AM251, … the cannabinoid CB1 receptor antagonist AM281 (3 mg·kg-1) …

[PDF][PDF] ANTI-ALLODYNIC AND ANTIHYPERALGESIC EFFECTS OF ZERUMBONE THROUGH INVOLVEMENT OF MONOAMINERGIC PATHWAYS IN MICE MODEL …

JCS MIN - 2018 - psasir.upm.edu.my
… The effect of TRPV1 and NMDA receptor antagonists co. administration with zerumbone on
1. determine the effective dosage of zerumbone in attenuating allodynia and hyperalgesia in …

… and meta-analysis of cannabinoids, cannabis-based medicines, and endocannabinoid system modulators tested for antinociceptive effects in animal models of injury …

N Soliman, S Haroutounian, AG Hohmann, E Krane… - Pain, 2021 - journals.lww.com
… frequently measured by attenuation of hypersensitivity to … system include selective synthetic
cannabinoid receptor agonists, … allodynia OR neuralgia OR hypersensitivity OR hyperalgesia

Photobiomodulation Therapy Improves Acute Inflammatory Response in Mice: the Role of Cannabinoid Receptors/ATP-Sensitive K+ Channel/p38-MAPK Signalling …

LMS Neves, ECD Gonçalves, J Cavalli, G Vieira… - Molecular …, 2018 - Springer
… Finally, evidences have shown that PBM attenuates nitro-oxidative … hyperalgesia induced
by ACEA was completely reversed by administration of AM251, a CB1 receptor antagonist, as …

[HTML][HTML] The nonopioid cholinergic agonist GTS-21 mitigates morphine-induced aggravation of burn injury pain together with inhibition of spinal microglia activation in …

Y Ren, Y Zhou, Z You, H Deng, WR Kem, J Mao… - British Journal of …, 2022 - Elsevier
attenuated by administration of α7AChR agonist, GTS-21. … of thermal hyperalgesia=0.8 and
mechanical allodynia=2.5 … with the α7AchR selective antagonist, methyllycaconitine. Using …